SELEX to Identify Protein-Binding Sites on RNA
نویسندگان
چکیده
منابع مشابه
SELEX to identify protein-binding sites on RNA.
SELEX (systematic evolution of ligands by exponential enrichment) is a very powerful method for determining the binding site of a protein on RNA. It relies on the ability of an RNA-binding protein to select high-affinity RNA ligands from a randomized pool of RNAs. SELEX experiments are performed over several "rounds," with each round resulting in increased enrichment of RNAs capable of binding ...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Protocols
سال: 2013
ISSN: 1559-6095
DOI: 10.1101/pdb.prot072934